According to a study done by BMJ, if anyone were to drink as much as James Bond does in all of Ian Fleming's books, he'd die by age 56 of liver cirrhosis.
The researchers went through all 14 James Bond novels and analyzed his alcohol use. His average consumption is 92 drinks per week which equates to more than 13 per day (4x as much as the maximum recommended amount).
Moreover, 007 had as many as 50 drinks per day. As the graphic below shows, his maximum consumption level is almost 226 drinks in "You Only Live Twice". On the other hand, the least he had was 41 drinks in "The Man With The Golden Gun" which was over a 3 day period (still a lot).
According to the study, this kind of alcohol usage would put James Bond in a very high risk category for organ damage. Moreover, they surmise these levels of drinking, he would probably not make it past the age of 56.
Furthermore, at these levels, there would also be some effects on brain which would certainly not help his expert driving, fighting and shooting skills.